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Bigger waist size holds clue to breast cancer type

Women with excessive abdominal fat are at risk of developing a type of breast cancer that is harder to treat compared with those who have general obesity or widespread fat accumulation, a study suggests.

Women with excessive abdominal fat are at risk of developing a type of breast cancer that is harder to treat compared with those who have general obesity or widespread fat accumulation, a study suggests

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Women with excessive abdominal fat are at risk of developing a type of breast cancer that is harder to treat compared with those who have general obesity or widespread fat accumulation, a study suggests.

Researchers in China examined medical data of 1,316 women aged 25-70 from 21 hospitals across the country who had been recently diagnosed with breast cancer.

They took body measurements and information on whether the women had been diagnosed with oestrogen-receptor positive (ER+) or the harder to treat negative (ER-) cancer.

Women with a high body mass index, providing a measure of subcutaneous fat on the thighs, hips and buttocks, were more likely to have ER+ breast cancers.

In contrast, women with a high waist-hip ratio, providing a measure of visceral fat (stomach and internal organs), were more likely to have ER- breast cancer.


Yu Z et al (2017) Distinct Effects of Body Mass Index and Waist/Hip Ratio on Risk of Breast Cancer by Joint Estrogen and Progestogen Receptor Status: Results from a Case‐Control Study in Northern and Eastern China and Implications for Chemoprevention. The Oncologist doi: org/10.1634/theoncologist.2017-0148

 

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