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High-fructose diet during and after pregnancy ‘can cause obesity in children’

A diet high in fructose-containing sugars during pregnancy or breastfeeding may increase children’s chances of developing obesity or type 2 diabetes, new study results suggest.

A diet high in fructose-containing sugars during pregnancy or breastfeeding may increase childrens chances of developing obesity or type 2 diabetes, new study results suggest.

The findings are contained in a new rat study published in The Journal of Physiology.

Offspring from mothers with a high fructose diet had detrimental fat content and composition in their livers, impacting negatively on metabolic health.

Researchers gave female rats water supplemented with fructose-containing sugars (sucrose or high fructose corn syrup) at an amount equivalent to those in standard soft drinks, before, during and after pregnancy.

Access to fructose

After birth, offspring were weaned by a mother with access to the same fructose-containing beverage, or by one with access to water only.

Body weight, fat mass and glucose control in the offspring were

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A diet high in fructose-containing sugars during pregnancy or breastfeeding may increase children’s chances of developing obesity or type 2 diabetes, new study results suggest.


A new study highlights the importance of maternal nutrition     Picture: Alamy

The findings are contained in a new rat study published in The Journal of Physiology.

Offspring from mothers with a high fructose diet had detrimental fat content and composition in their livers, impacting negatively on metabolic health.

Researchers gave female rats water supplemented with fructose-containing sugars (sucrose or high fructose corn syrup) at an amount equivalent to those in standard soft drinks, before, during and after pregnancy.

Access to fructose

After birth, offspring were weaned by a mother with access to the same fructose-containing beverage, or by one with access to water only.

Body weight, fat mass and glucose control in the offspring were measured and tissues were analysed to see the amount and type of fat in their livers.

University of South Australia senior lecturer and lead study investigator Sheridan Gentili said the study highlighted the importance of maternal nutrition during the lactation period.


Gentili S et al (2017) Impact of perinatal exposure to sucrose or high fructose corn syrup (HFCS-55) on adiposity and hepatic lipid composition in rat offspring. Journal of Physiology. doi 10.1113/JP274066
 

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