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Steroid use could help prevent childhood stroke

Trialled use of steroids to prevent childhood stroke is justified, concludes an extensive review of recent reports.
Stroke

Trialled use of steroids to prevent childhood stroke is justified, concludes an extensive review of recent reports.

Although there is little evidence about the prevention or treatment of arterial ischaemic stroke (AIS) in children, drugs that regulate the immune and inflammatory response could prevent occurrence or recurrence.

This Archives of Disease in Childhood report concerns immunotherapy among patients with arteriopathy or acute infection. Drawing on 32 observational studies and two trials in the Embase and Medline databases, the report considers relevant case reports, trials, cohorts and cross-sectional studies.

The authors found that steroids were used in 80% of the case studies and recurrence rates were low.

They also identified an association between patient use of steroids and

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