Short-term corticosteroid use associated with increased risk of adverse events
Study aims to determine the frequency of serious adverse events associated with corticosteroid use – specifically sepsis, VTE and fracture
Corticosteroids are powerful anti-inflammatory drugs that have been used to treat a variety of diseases since their introduction for rheumatoid arthritis in 1949. A strong driver for corticosteroid use is their symptomatic relief.
Long-term use is generally avoided, because of serious acute complications such as infection, venous thromboembolism (VTE) and fracture as well as chronic diseases such as diabetes mellitus, hypertension and osteoporosis. Adverse events as a result of corticosteroids are one of the most common reasons for admission to hospital.
In contrast with long-term use, the risk from short-term use is much less understood. Brief courses are often used to treat inflammatory conditions such as asthma, inflammatory bowel disease, rheumatoid...
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