Journal scan

Low LDL cholesterol levels may reduce risk of Alzheimer’s disease

Latest research from the nursing and medical journals.
Statins

Latest research from the nursing and medical journals.

Patients at high risk of cardiovascular disease are recommended to reduce their low-density lipoprotein (LDL) levels to less than 2.6mmol/L, while those at very high risk are advised to reduce levels to less than 1.8mmol/L.

However, cholesterol is a major constituent of the brain, especially the myelin encircling neurons. Some research suggests that the risk of neurological diseases, such as Alzheimer’s disease and Parkinson’s disease, increases in people treated with cholesterol-lowering drugs such as statins.

This article suggests that such research may suggest an increased risk because people change their lifestyle after neurological problems develop so that a decrease in LDL levels is a result, not a cause, of neurological changes.

The authors studied people with a genetic predisposition to low cholesterol to see if they had higher

...

Want to read more?

Unlock full access to RCNi Plus today

Save over 50% on your first three months:

  • Customisable clinical dashboard featuring 200+ topics
  • Unlimited online access to all 10 RCNi Journals including Nursing Older People
  • RCNi Learning featuring 180+ RCN accredited learning modules
  • NMC-compliant RCNi Portfolio to build evidence for revalidation
  • Personalised newsletters tailored to your interests

This article is not available as part of an institutional subscription. Why is this?

Jobs