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Fragile X and autism: treatments for hypersensitivity

Potential new research developments to improve sensory stimulation.
Fragile X chromosomes

Potential new research developments to improve sensory stimulation

It is recognised that people with fragile X and autism share common needs. In both conditions, for example, individuals can respond too readily to sensory stimulation, in the case of people with fragile X especially, this oversensitivity is due to overexcitement of the neurones. The overstimulation of the neuronal pathways leads to seizures and sensory hypersensitivity.

A protein – mGluR 5 – has been found to be in excess in individuals who have excitable neurones. Previous research has been attempted to inhibit overstimulation, but the treatments have failed to manipulate the protein itself. New developments however, have the potential for providing improvements.

Research is now being undertaken which aims to manipulate the module responsible for developing the mGluR 5 protein, therefore influencing the production of the protein before it is

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